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Pharmacology

Comprehensive studies that elucidate pharmacodynamics, mechanism of action, and efficacy of candidate compounds. In vivo and in vitro studies are conducted with utmost care and compliance with best industry practice.

Home Services & Solutions Discovery Pharmacology Metabolic

Metabolic

Metabolic Diseases Animal Models

High fat diet induced obese (DIO) rats/mice

Streptozotocin (STZ) induced type 1 diabetic rats/mice

High fat diet (HFD) + STZ induced type 2 diabetic rats/mice

KKAy mice with T2D complications such as retinopathy & nephropathy

ob/ob and db/db mice

Myocardial infarction and reperfusion injury in rats/mice

Renal ischemia and reperfusion injury in rats/mice

DOCA rat model

DSS rat model

In Vivo Assays

Oral/intraperitoneal glucose, insulin and pyruvate tolerance tests

Glucagon challenge tests

Energy expenditure indirect calorimetry system (TSE)

Food intake and water intake monitoring

Urine and feces collection

Body fat and water composition by echoMRI

Chemistry
Medicinal Chemistry Parallel Synthesis Peptide Chemistry Computational Chemistry Synthetic Chemistry Analytical Chemistry Scale Up Chemistry
Drug Metabolism and Pharmacokinetics (DMPK)
In Vivo PK and TK In Vitro ADME Bioanalytical Service Toxicity In Rodents, Dogs and Monkeys Large Molecule Development and Bioanalysis
Discovery Biology
Fragment Based Drug Discovery (FBDD) Biochemical Assays Cellular Assays Protein Science Assay Technologies Biophysics SPR Safety Pharmacology Screening Services Key Instruments
Oncology
PDX CDX Orthotopic Models Syngeneic Models Humanized Mouse Models CAR-T and CAR-NK Mouse Models In Vitro Assays
Pharmacology
Immunology Inflammation Metabolic MASH Mouse Models Respiratory Neuroscience
Biologics
Systematic Antibody Discovery Service
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