High quality in vitro and in vivo studies to help prediction of therapeutic outcomes. Integration with early formulation development studies that enable more accurate scaling of results to humans.
BioDuro-Sundia provides insightful Drug Metabolism and Pharmacokinetics services through its unique position as a drug discovery and preclinical development organization. With strong credentials and experience, as well as collaborating internally with medicinal chemistry, biology, pharmacology, oncology and formulation development, the DMPK team performs various in vitro and in vivo assays to evaluate the absorption, distribution, metabolism and excretion (ADME), and pharmacokinetics (PK) properties of drug candidates during lead finding and optimization, subsequently preclinical candidate (PCC) nomination and IND-enabling (investigational new drug) ADME and PK studies for regulatory filing studies for various new chemical entities (NCEs).
Assay platform spanning from discovery to preclinical development
The state-of-the-art and GLP-like bioanalytical laboratory
AAALAC accredited animal facilities
Over 16-year history of execution, flexibility and timeliness
Rapid turnaround time
In Vivo PK/TK
In Vitro ADME
Discovery and GLP-like Bioanalytical Method Development, Validation and Sample Analysis
Exploratory Toxicity in Rodents, Dogs and Monkeys
Comprehensive LC-MS/MS Instruments for Bioanalysis