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Discovery Biology

Cutting edge technologies supporting a broad array of services including discovery, preclinical and translational assays.

Home Services & Solutions Discovery Discovery Biology Biochemical Assays

Biochemical Assays

Biochemical assays are typically conducted earlier in the drug discovery process to identify promising candidates, followed by in vitro assays to assess the candidates' biological activity.
Enzymatic Assays

Kinase

Phosphatase

Protease

GTPase

Oxidase

Hydrolase

Carboxylase

Nucleotidase

DNA polymerase

Phosphohydrolyase

Nicotinamide

Phosphoribosyltransferase

GPCR Related Assays

³H– labeled ligand binding assay

SPA assay

Fluorescence polarization assay

Epigenetics Related Assays

Writers

Histone methyltransferase

Histone acetyltransferase

Protein arginine methyltransferase: eg. MTA-cooperative PRMT5 assays

RNA modification gene: eg. METTL3/14 assay

Poly(ADP)-ribose polymerase: PARPs

Erasers

Demethylase: eg. HDACs, KDMs

Deubiquitinase: eg. DUB

Readers

Bromo domain containing protein binding partner assays: eg. BRDs

Chemistry
Medicinal Chemistry Parallel Synthesis Peptide Chemistry Computational Chemistry Synthetic Chemistry Analytical Chemistry Scale Up Chemistry
Drug Metabolism and Pharmacokinetics (DMPK)
In Vivo PK and TK In Vitro ADME Bioanalytical Service Toxicity In Rodents, Dogs and Monkeys Large Molecule Development and Bioanalysis
Discovery Biology
Fragment Based Drug Discovery (FBDD) Biochemical Assays Cellular Assays Protein Science Assay Technologies Biophysics SPR Safety Pharmacology Screening Services Key Instruments
Oncology
PDX CDX Orthotopic Models Syngeneic Models Humanized Mouse Models CAR-T and CAR-NK Mouse Models In Vitro Assays
Pharmacology
Immunology Inflammation Metabolic MASH Mouse Models Respiratory Neuroscience
Biologics
Systematic Antibody Discovery Service
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