METABOLIC
Comprehensive studies that elucidate pharmacodynamics, mechanism of action, and efficacy of candidate compounds. In vivo and in vitro studies are conducted with utmost care and compliance with best industry practice.
Respiratory Disease Models
Metabolic Diseases Animal Models
- High fat diet induced obese (DIO) rats/mice
- Streptozotocin (STZ) induced type 1 diabetic rats/mice
- High fat diet (HFD) + STZ induced type 2 diabetic rats/mice
- KKAy mice with T2D complications such as retinopathy & nephropathy
- ob/ob and db/db mice
- Myocardial infarction and reperfusion injury in rats/mice
- Renal ischemia and reperfusion injury in rats/mice
In Vivo Assays
- Oral/intraperitoneal glucose, insulin and pyruvate tolerance tests
- Glucagon challenge tests
- Energy expenditure indirect calorimetry system (TSE)
- Food intake and water intake monitoring
- Urine and feces collection
- Insulin level detection
- Body fat and water composition by echoMRI