Cellular Assays
Cutting edge technologies supporting a broad array of services including cell line & antibody reagent generation and target validation.
Cellular Assays
Immunology and Inflammation assays on cell lines, primary cells, hWB, PBMC, T cell, B cell, and other immune cells
- Immunology and Inflammation assays on cell lines, primary cells, hWB, PBMC, T cell, B cell, and other immune cells
- Oncology assays
- CTG (2D or 3D)/MTT/CCK8/LDH/CyQuant/SRB/Caspase 3&7/PI-Annexin V/BrdU
- Migration, Invasion
- cAMP and IP-1 assays
- Calcium flux assays
- Reporter gene assays (Luciferase, β-lac, GFP, β-gal, etc.)
- Membrane potential and Thallium flux assays
- Uptake assays
- Ion Channel assays (80+ targets, Qpatch and manual patch clamp)
- Comprehensive in vitro Proarrhythmia Assay (CiPA)
IMMUNOLOGY & IMMUNO-ONCOLOGY
- Immuno-Oncology
- PBMC, T cell, B cell and NK cell isolation
- T cell activation and proliferation assays
- Immuno-phenotyping or biomarkers analysis with multi-color FACS
- Antibody-dependent cell-mediated cytotoxicity (ADCC)
- T-cell infiltration into 3D tumor cell spheroids
- Immunocytes cytotoxicity to cancer cells
- Immune/Cancer Mixed Culture
ION CHANNELS
- Voltage gated sodium channels
- Voltage gated calcium channels
- Potassium channels
- TRP channels
- Ligand gated ion channels
METABOLIC & LIPID DISEASES
- In vitro Assays for Metabolic & Lipid Diseases
- Phenotypic Functional Assays
- Primary hepatocyte isolation
- Adipocyte differentiation
- Lipogenesis assay 3H-Acetate)
- Glucose uptake (colorimetric)
- FA uptake (fluorometric)
- Lipase activity assay
- Beta-Oxidation (3-hydroxybutyric acid level)
- Biomarker Analysis
- Insulin level detection
- Blood glucose, blood lipid level, Liver & kidney function analysis:
- CHO, TG, HDL, LDL, BUN, CRE, ALT, AST
- Fibrotic markers:
- Collagen type 1a, 3a levels
- TGF-b expression levels
- Hydroxyproline levels
- SMA-a levels
- NAFLD/NASH Models