Biophysics spr
Cutting edge technologies supporting a broad array of services including cell line & antibody reagent generation and target validation.
Biophysics: SPR
Surface plasmon Resonance (SPR) is a core Biophysical technique used at BioDuro. We have a state-of-the-art SPR system, Biacore 8K (GE), at our Shanghai site.
SPR for Biologics
- Affinity Maturation
- Hot Spot Analysis/Stress Test
- Fc Engineering
- Anti-drug Antibodies (ADA)
- Epitope Binning/Mapping
- BsAb Construction
- CAR-T scFv Screening and Selection
- Antibody-Drug Conjugate (ADC)
- Epitope Mapping
- IND Package
- Specificity Study
- Cross-Reactivity
- FcRn
- FcγRs
- C1Q
SPR for NCE
- Compound binding affinity
- Full binding kinetics and binding stoichiometry
- Residence time
- Fragment library screening